pentobarbital decreases levels of ponatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Steer clear of Except the coadministration outweighs the achievable chance of ponatinib underexposure; observe for indications of decreased efficacy.
Pretreatment with or concurrent administration of phenobarbital may possibly reduce the influence of estradiol by raising its metabolism. There happen to be studies of sufferers addressed with antiepileptic drugs (e.
pentobarbital will lessen the extent or impact of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
pentobarbital will minimize the level or effect of ritonavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the level or outcome of nelfinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lower the extent or impact of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Powerful CYP3A4 inducers are envisioned to trigger considerable decreases in sildenafil plasma concentrations
pentobarbital will lessen the extent or outcome of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Loss of, or diminished response to tofacitinib may possibly manifest when coadministered with powerful CYP3A4 inducers
pentobarbital will decrease the extent or impact of carvedilol by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Check.
pentobarbital will minimize the level or influence of irinotecan by impacting hepatic/intestinal enzyme click here CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the extent or outcome of amiodarone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the extent or result of vinorelbine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Mysterious.
pentobarbital will reduce the extent or impact of copyright topical by influencing hepatic enzyme CYP2B6 metabolism. Small/Importance Unknown.
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pentobarbital will lessen the level or outcome of capivasertib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Robust or average CYP3A inducers reduce capivasertib publicity, which may lessen efficacy.